PUBLICACIONES

PUBLICACIONES 2021

Preparation, physicochemical and biopharmaceutical characterization of oxcarbazepine-loaded nanostructured lipid carriers as potential antiepileptic devices

S.Scioli Montotoa G.Muracaab M.Di Iannia M.Couyoupetrouab G.Pesceb G.A.Islanc C.Y.Chaind M.E.Velad M.E.Ruiza A.Talevia G.R.Castroce

aLaboratorio de Investigación y Desarrollo de Bioactivos (LIDeB), Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP), Calle 47 y 115 (B1900AJI), La Plata, Buenos Aires, Argentina
bDepartamento de Farmacología, Instituto Nacional de Medicamentos (INAME), Administración Nacional de Medicamentos, Alimentos y Tecnología Médica (ANMAT), CABA, Buenos Aires, Argentina
cLaboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP) -CONICET (CCT La Plata), Calle 47 y 115, (B1900AJI), La Plata, Buenos Aires, Argentina
dInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), CONICET-UNLP, CC 16 Suc 4, La Plata, 1900, Buenos Aires, Argentina
eMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC). Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG). Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000, Rosario, Santa Fe, Argentina

Received 24 November 2020, Revised 23 February 2021, Accepted 3 March 2021, Available online 6 March 2021.
https://doi.org/10.1016/j.jddst.2021.102470

Editorial: Lipid Nanoparticles as a Novel Strategy to Deliver Bioactive Molecules

Alan Talevi1,2*, Nelson Duran3 and Guillermo Raul Castro1

  • 1Laboratory of Bioactive Research and Development (LIDeB), Department of Biological Sciences, Faculty of Exact Sciences, University of La Plata (UNLP), La Plata, Argentina
  • 2Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina
  • 3Laboratory of Urogenital Carcinogenesis andImmunotherapy, Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil
  • 4Laboratorio de Nanobiomateriales, Centro de Investigacióny Desarrollo enFermentaciones Industriales (CINDEFI), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional deLa Plata (UNLP)-CONICET (CCT La Plata), La Plata, Argentina

Front. Chem., 04 March 2021
https://doi.org/10.3389/fchem.2021.655480



Design of magnetic hybrid nanostructured lipid carriers containing 1,8-cineole as delivery systems for anticancer drugs: Physicochemical and cytotoxic studies

B.Rodenak-Kladniewa N.Noaccob I.Pérez de Bertic S.J.Stewartd A.F.Cabrerad V.A.Alvareze M.García de Bravoa N.Duránfg G.R.Castrobh G.A.Islanb

aInstituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), CONICET-UNLP, CCT-La Plata, Facultad de Ciencias Médicas, La Plata, Argentina
bLaboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP) -CONICET (CCT La Plata), Calle 47 y 115, B1900AJI, La Plata, Buenos Aires, Argentina
cCINDECA, CONICET-CICPBA-Universidad Nacional de La Plata, Facultad de Ciencias Exactas, Calle 47 N 257, 1900, La Plata, Argentina
dIFLP-CONICET, Departamento de Física, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, C. C. 67, 1900, La Plata, Argentina
eGrupo de Materiales Compuestos Termoplásticos (CoMP), Instituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA), Facultad de Ingeniería, Universidad Nacional de Mar del Plata (UNMdP) y Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Av. Colón 10850, 7600, Mar del Plata, Argentina
fLaboratory of Urogenital Carcinogenesis and Immunotherapy, Department of Structural and Functional Biology, Biology Institute, University of Campinas, Campinas, SP, Brazil
gNanomedicine Research Unit (Nanomed), Federal University of ABC (UFABC), Santo André, SP, Brazil
hMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC). Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG). Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000, Rosario, Santa Fe, Argentina

Received 1 July 2020, Revised 9 February 2021, Accepted 16 March 2021, Available online 19 March 2021.
https://doi.org/10.1016/j.colsurfb.2021.111710


Improving ciprofloxacin antimicrobial activity through lipid nanoencapsulation or non-thermal plasma on Pseudomonas aeruginosa biofilms

Giuliana S.Muracaa JulianaSoler-Arangoa Guillermo R.Castrobc Germán A.Islanb GracielaBrelles-Mariñoa

aBiofilm Eradication Laboratory. Centro de Investigación y Desarrollo en Fermentaciones Industriales, Consejo Nacional de Investigaciones Científicas y Técnicas (CINDEFI, CCT-LA PLATA-CONICET), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, ArgentinabLaboratorio de Nanobiomateriales – CINDEFI (CCT-LA PLATA-CONICET), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, ArgentinacMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC). Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG). Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000 Rosario, Santa Fe, Argentina

Received 29 October 2020, Revised 26 May 2021, Accepted 29 May 2021, Available online 9 June 2021.
https://doi.org/10.1016/j.jddst.2021.102644

Lipid, polymeric, inorganic-based drug delivery applications for platinum-based anticancer drugs

TugceBoztepeaGuillermo R.CastroabIgnacio E.Leónc

aLaboratorio de Nanobiomateriales, CINDEFI – Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata-CONICET (CCT La Plata), Calle 47 y 115, B1900AJL La Plata, ArgentinabMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC), Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG), Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000 Rosario, Santa Fe, ArgentinacCentro de Química Inorgánica, CEQUINOR (CONICET-UNLP), Bv. 120 1465, La Plata, Argentina

Received 15 December 2020, Revised 2 June 2021, Accepted 5 June 2021, Available online 9 June 2021.
https://doi.org/10.1016/j.ijpharm.2021.120788

Patents on Violacein: A Compound with Great Diversity of Biological Activities and Industrial Potential

Nelson Durán 1Wagner J Fávaro 1Marcelo Brocchi 2Giselle Z Justo 3Guillermo R Castro 4Marcela Durán 1Gerson Nakazato 5

  • 1Laboratory of Urogenital Carcinogenesis and Immunotherapy, Biology Institute, Department of Structural and Functional Biology, University of Campinas,Campinas, SP. Brazil.
  • 2Laboratory of Tropical Diseases, Institute of Biology, Department of Genetic, Evolution, Microbiology and Immunology. University of Campinas, Campinas, SP. Brazil.
  • 3Department of Pharmaceutical Sciences and Department of Biochemistry, Federal University of São Paulo (UNIFESP). Brazil.
  • 4Nanobiomaterials Laboratory, Institute of Applied Biotechnology CINDEFI (UNLP-CONICET, CCT La Plata), Department of Chemistry, School of Sciences, Universidad Nacional de La Plata, La Plata. Argentina.
  • 5Laboratory of Basic and Applied Bacteriology, Department of Microbiology, Biology Sciences Center, Londrina State University (UEL), Londrina. Brazil.

PMID: 33349223 DOI: 10.2174/2213476X07666201221111655

Isolation and partial characterization of Komagataeibacter spSU12 and optimization of bacterial cellulose production using Mangifera indica extracts

Calderón-Toledo S., Horue M., Alvarez V.A., Castro G.R., Zavaleta A.I. (2021)
Journal of Chemical Technology and Biotechnology
In press. DOI: 10.1002/jctb.6839. (ISSN: 0268-2575). IF: 3.174.

Multi-target drug with potential applications: A spot on violacein

Durán N., Nakazato G., Durán M., Rivero Berti I., Castro G.R., Stanisic D., Brocchi M., Fávaro W.J., Ferreira-Halder C.V., Zenker Justo G., Tasic L. 
2021
World Journal of Microbiology and Biotechnology. Accepted. (ISSN: 0959-3993). IF:2.477.

Microbial production and recovery of hybrid biopolymers from wastes for industrial applications- a review

Laboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP) -CONICET (CCT La Plata), Calle 47 y 115, (B1900AJI), La Plata, Buenos Aires, ArgentinabChildren’s Hospital, University Medical Center, Johannes Gutenberg-University, Mainz, GermanycMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC). Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG). Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000 Rosario, Santa Fe, Argentina

Received 31 May 2021, Revised 23 July 2021, Accepted 24 July 2021, Available online 27 July 2021.

https://doi.org/10.1016/j.biortech.2021.125671

Bioresource Technology
Volume 340, November 2021, 125671

Ecotoxicologic effects of silver nanoparticles on freshwater nontarget species

Natalı´ Romero1,2, Guillermo R. Castro2,3,4, Ana Marı´a Gagneten1
1Laboratorio de Ecotoxicologia, Departamento de Ciencias Naturales, Facutad de Humanidades y
Ciencias, Universidad Nacional del Litoral, (FHUC, UNL), Santa Fe, Argentina; 2Consejo Nacional
de Investigaciones Cientı´ficas y Te´cnicas (CONICET), Argentina; 3Laboratorio de
Nanobiomateriales, CINDEFI e Depto. de Quı´mica, Facultad de Ciencias Exactas, Universidad de
La Plata e CONICET (CCT La Plata), La Plata, Buenos Aires, Argentina; 4Max Planck
Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR,
UNR-MPIbpC), Partner Laboratory of the Max Planck Institute for Biophysical Chemistry
(MPIbpC, MPG), Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario,
Maipu´, Rosario, Santa Fe, Argentina

ISBN: 978-0-12-822965-1

New Trends in Removal of Heavy Metals from Industrial Wastewater
Chapter 28

Copyright © 2021 Elsevier Inc.

Simultaneous electrochemical detection of ciprofloxacin and Ag(I) in a
silver nanoparticle dissolution: Application to ecotoxicological
acute studies

Silvina V. Kergaravat a,b,*, Natalí Romero a, Luciana Regaldo a, Guillermo R. Castro c,d, Silvia
R. Hernández b, Ana María Gagneten a

a Laboratorio de Ecotoxicología, Facultad de Humanidades y Ciencias, Universidad Nacional del Litoral (UNL), UNL-CONICET, CCT Santa Fe, 3000 Santa Fe, Argentina
b Laboratorio de Sensores y Biosensores, Facultad de Bioquímica y Ciencias Biológicas, UNL-CONICET, CCT Santa Fe, 3000 Santa Fe, Argentina
c Laboratorio de Nanobiomateriales, CINDEFI – Facultad de Ciencias Exactas (UNLP – CONICET, CCT La Plata), La Plata 1900, Argentina
d Laboratorio Max Planck de Biología Estructural, Química y Biofísica Molecular de Rosario (MPLbioR, UNR-MPIbpC), Laboratorio Asociado del Instituto Max Planck
para Química Biofísica (MPIbpC, MPG), Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000 Rosario, Santa Fe, Argentina

* Corresponding author: E-mail address: skergaravat@fbcb.unl.edu.ar (S.V. Kergaravat).

https://doi.org/10.1016/j.microc.2020.105832

Received 29 June 2020; Received in revised form 29 October 2020; Accepted 20 November 2020, Available online 11 December 2020

0026-265X/© 2020 Elsevier B.V.

Physiological and morphological responses of green microalgae Chlorella
vulgaris to silver nanoparticles

Natalí Romero a,b, Flavia F. Visentini b,d, Vanina E. Máarquez e, Liliana G. Santiago b,d,
Guillermo R. Castro c, Ana M. Gagneten a,*

a Laboratorio de Ecotoxicología, Facultad de Humanidades y Ciencias, Universidad Nacional del Litoral, Ciudad Universitaria – Paraje El Pozo S/n (3000), Santa Fe,
Argentina
b CONICET, Predio CONICET “Dr. Alberto Cassano”, Colectora Ruta Nac. Nº 168, Km. 0, Paraje El Pozo (3000), Santa Fe, Argentina
c Laboratorio de Nanobiomateriales, CINDEFI – Departamento de Química – Facultad de Ciencias Exactas, Universidad Nacional de La Plata – CONICET (CCT La Plata),
Calle 50 Nº 227, La Plata, 1900, Buenos Aires, Argentina
d Area de Biocoloides y Nanotecnología, Instituto de Tecnología de Alimentos (ITA), Facultad de Ingeniería Química (FIQ), Universidad Nacional del Litoral (UNL),
Santiago Del Estero 2829, Santa Fe, Argentina
e Laboratorio de Fermentaciones, Facultad de Bioquímica y Ciencias Biolóogicas, Universidad Nacional del Litoral, Ciudad Universitaria – Paraje El Pozo S/n (3000),
Santa Fe, Argentina
* Corresponding author: E-mail address: amgagneten@fhuc.unl.edu.ar (A.M. Gagneten).

https://doi.org/10.1016/j.envres.2020.109857
Received 15 April 2020; Received in revised form 29 May 2020; Accepted 12 June 2020, Available online 11 July 2020
0013-9351/© 2020 Elsevier Inc.

Silver nanoparticle flter for domestic wastewater reuse

Ana M Gagneten, a* Natalí Romero,a,b Ulises Reno,a,b Luciana Regaldo,a,b
Silvina V Kergaravat,a,b,c Boris E Rodenak-Kladniewd and
Guillermo R Castroe,f*

a Laboratorio de Ecotoxicología, Facultad de Humanidades y Ciencias, Universidad
Nacional del Litoral, Santa Fe, Argentina
b Consejo Nacional de Investigaciones Cientícas y Técnicas (CONICET), Santa
Fe, Argentina
c Laboratorio de Sensores y Biosensores, Facultad de Bioquímica y Ciencias Biológicas,
Universidad Nacional del Litoral, Santa Fe, Argentina
d Facultad de Ciencias Médicas, Instituto de Investigaciones Bioquímicas de La
Plata (INIBIOLP), CONICET-UNLP, CCT-La Plata, La Plata, Argentina
e Laboratorio de Nanobiomateriales, CINDEFI, Departamento de Química,
Facultad de Ciencias Exactas, Universidad Nacional de La Plata – CONICET
(CCT La Plata), Buenos Aires, Argentina
f Max Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics
of Rosa rio (MPLbioR, UNR-MPIbpC), Partner Laboratory of the Max
Planck Institute for Biophysical Chemistry (MPIbpC, MPG), Centro de Estudios
Interdisciplinarios (CEI), Universidad Nacional de Rosario, Rosario, Argentina

Received: 23 December 2020 Revised: 25 February 2021 Accepted article published: 2 March 2021 Published online in Wiley Online Library

DOI 10.1002/jctb.6710

https://onlinelibrary.wiley.com/

PUBLICACIONES 2020

Physiological and morphological responses of green microalgae Chlorella vulgaris to silver nanoparticles

Natalí Romero (a)(b), Flavia F. Visentini (b)(d), Vanina E. Márquez (e),Liliana G. Santiago (b)(d), Guillermo R. Castro (c) ,Ana M. Gagneten (a)

(a) Laboratorio de Ecotoxicología, Facultad de Humanidades y Ciencias, Universidad Nacional del Litoral, Ciudad Universitaria – Paraje El Pozo S/n (3000), Santa Fe, Argentina
(b) CONICET, Predio CONICET “Dr. Alberto Cassano”, Colectora Ruta Nac. Nº 168, Km. 0, Paraje El Pozo (3000), Santa Fe, Argentina
(c) Laboratorio de Nanobiomateriales, CINDEFI – Departamento de Química – Facultad de Ciencias Exactas, Universidad Nacional de La Plata – CONICET (CCT La Plata), Calle 50 Nº 227, La Plata, 1900, Buenos Aires, Argentina
(d) Área de Biocoloides y Nanotecnología, Instituto de Tecnología de Alimentos (ITA), Facultad de Ingeniería Química (FIQ), Universidad Nacional del Litoral (UNL), Santiago Del Estero 2829, Santa Fe, Argentina
(e) Laboratorio de Fermentaciones, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Ciudad Universitaria – Paraje El Pozo S/n (3000), Santa Fe, Argentina

Received 15 April 2020, Revised 29 May 2020, Accepted 12 June 2020, Available online 11 July 2020.

DOI: https://doi.org/10.1016/j.envres.2020.109857

Environmental Research, Volume 189, October 2020, 109857

Assessment of in vitro cytotoxicity of imidazole ionic liquids and inclusion in targeted drug carriers containing violacein

Ignacio Rivero Berti (a), Boris Rodenak-Kladniew (b), Celeste Onaindia (c), Claudia G. Adam (c), German A. Islan (a), Nelson Durán (d e) and Guillermo R. Castro (a)

(a) Laboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata-CONICET (CCT La Plata), Calle 47 y 115, B1900AJL La Plata, Argentina
E-mail: grcastro@gmail.com
(b) Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), CONICET-UNLP, CCT-La Plata, Facultad de Ciencias Médicas, B1900 La Plata, Argentina
(c) IQAL, Instituto de Química del Litoral (UNL-CONICET), Facultad de Ingeniería Química-Universidad Nacional del Litoral, Santiago del Estero 2829, Santa Fe, Argentina
(d) Institute of Biology, Universidade Estadual de Campinas, C.P. 6159, Campinas, SP, Brazil
(e) NanoMed Center, Federal University of ABC (UFABC), Santo André, SP, Brazil
DOI: http://xlink.rsc.org/?DOI=d0ra05101b
Issue 49, 2020

Design of nalidixic acid‑vanadium complex loaded into chitosan hybrid nanoparticles as smart strategy to inhibit bacterial growth and quorum sensing

Author links open overlay panelBárbara Bueloni(a), Daniele Sanna(b), Eugenio Garribba(c), Guillermo R. Castro(a), Ignacio E. León(d), Germán A. Islan(a)

(a) Laboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP) -CONICET (CCT La Plata), Calle 47 y 115, B1900AJI La Plata, Buenos Aires, Argentina
(b) Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, trav. la Crucca 3, 07100 Sassari, Italy
(c) Dipartimento di Chimica e Farmacia, Unversità di Sassari, Via Vienna 2, 07100 Sassari, Italy
(d) Centro de Química Inorgánica (CEQUINOR, UNLP-CONICET, CCT La Plata), Universidad Nacional de La Plata, Bv 120 1465, La Plata, Argentina.

DOI: https://doi.org/10.1016/j.ijbiomac.2020.07.304
Available online 7 August 2020

Antimicrobial activities of bacterial cellulose – Silver montmorillonite
nanocomposites for wound healingassessment

Manuel Horue(a), Maximiliano L. Cacicedo (a), Mariela A. Fernandez (b), Boris Rodenak-Kladniew (c), Rosa M. Torres Sánchez (b),⁎, Guillermo R. Castro (a),⁎
(a) Laboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata-CONICET (CCT La Plata), Calle 47 y 115, B1900AJL La Plata, Argentina
(b) Centro de Tecnología de recursos Minerales y Cerámica (CETMIC, CIC-CONICET CCT La Plata), Camino Centenario y 506, (1897), M.B. Gonnet, Argentina
(c) Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP, CONICET-UNLP, CCT La Plata), Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina
⁎ Corresponding authors:
E-mail addresses: rosats@cetmic.unlp.edu.ar (R.M. Torres Sánchez), grcastro@quimica.unlp.edu.ar (G.R. Castro).

DOI https://doi.org/10.1016/j.msec.2020.111152:

Available online 10 June 2020
0928-4931/ © 2020 Published by Elsevier B.V.

PUBLICACIONES 2019

Bio-inks for 3D extrusion-based bio-printed scaffolds: Printability
assessment

Verónica E. Passamai (a), ; Sergio Katz (a), Vera Alvarez (b), Guillermo R. Castro (a)*
(a) Nanobiomaterials Lab, CINDEFI, School of Sciences, National University of La Plata-CONICET (CCT La Plata), Buenos Aires, Argentina
(b) Grupo de Materiales Compuestos Termoplásticos (CoMP), Instituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA), Facultad de Ingeniería, Universidad Nacional de Mar del Plata (UNMDP) – CONICET, Av. Colón 10850 (B7608FDQ), Mar del Plata, Buenos Aires,
Argentina.

DOI: https://doi.org/10.25061/2595-3931/IJAMB/2019.v2i1.43

Volume 2, N 1, March-September, pag. 43 -45

Development and characterization of an improved formulation of cholesteryl oleate-loaded cationic solid-lipid nanoparticles as an efficient non-viral gene delivery system

María J. Limeres (a,b,c) , Marc Suñé-Poua (b)⁎⁎, Silvia Prieto-Sánchez (b), Cristina Moreno-Castro(b),
Alejandro D. Nusblat(d), Cristina Hernández-Munain(e), Guillermo R. Castro(f), Carlos Suñé(b),
Josep M. Suñé-Negre(a), María L. Cuetsas (c,⁎)
a Service of Development of Medicines (SDM), Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
b Department of Molecular Biology, Institute of Parasitology and Biomedicine “López-Neyra” (IPBLN-CSIC), Granada, Spain
c Institute of Research in Microbiology and Medical Parasitology (IMPaM), Faculty of Medicine, University of Buenos Aires-CONICET, Buenos Aires, Argentina
d Institute of Nanobiotechnology (NANOBIOTEC), Faculty of Pharmacy and Biochemistry, University of Buenos Aires-CONICET, Buenos Aires, Argentina
e Department of Cell Biology and Immunology, Institute of Parasitology and Biomedicine “López-Neyra” (IPBLN-CSIC), Granada, Spain
f Nanobiomaterials Lab, CINDEFI, School of Sciences, National University of La Plata-CONICET (CCT La Plata), Buenos Aires, Argentina

https://doi.org/10.1016/j.colsurfb.2019.110533

Colloids and Surfaces B: Biointerfaces
Volume 184, 1 December 2019, 110533

Lipid nanoparticles – Metvan: revealing a novel way to deliver a vanadium compound to bone cancer cells

M. L. Cacicedo, M. C. Ruiz, S. Scioli-Montoto, M. E. Ruiz, M. A. Fernández, R. M. Torres-Sanchez, E. J. Baran, G. R. Castro and I. E. León
New Journal of Chemistry
July 2019

Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties

B.Rodenak-Kladniew, S.Scioli Montotob, M.L.Sbaraglini, M.Di Ianni, M.E.Ruiz, A.Talevi, V.A.Alvarez, N.Duránd, G.R.Castro, G.A.Islan
International Journal of Pharmaceutics
Volume 569, July 2019

Silybin-conjugated gold nanoparticles for antimicrobial chemotherapy against Gram-negative bacteria

German A.Islan,  Suvadra Das, Maximiliano L.Cacicedo,  Asim Halder, Asmita Mukherjee, María Luján Cuestas, Partha Roy , Guillermo R.Castro, Arup Mukherjeed
Journal of Drug Delivery Science and Technology
Volume 53, July2019

Formation and characterization of self-assembled bovine serum albumin nanoparticles as chrysin delivery systems

Ferrado J.B., Perez A.A., Visentini F.V., Islan G.A., Castro G.R., Santiago L
Colloids and Surfaces B: Biointerfaces
Volume 173, 1 January 2019, Pages 43-51

A new glioblastoma cell trap for implantation after surgical resection

Autier L., Clavreul A., Cacicedo M.L., Franconi F., Sindji L., Rousseau A., Perrot R., Montero-Menei C.N., Castro G.R., Menei P
Acta Biomaterialia
Volume 84, 15 January 2019, Pages 268-279

Development of biocarrier for violacein controlled release in the treatment of cancer

Rivero Berti I., Rodenak-Kladniew B., Pérez A.A., Santiago L., Duran N., Castro G.R
Reactive and Functional Polymers
Volume 136, March 2019, Pages 122-130

Immobilized enzymes and their applications

Cacicedo M.L., Manzo R.M., Municoy S., Bonazza H.L., Islan G.A., Desimone M., Bellino M., Mammarella E.J., Castro G.R.
In: Advances in Enzyme Technology. Ram S. Singh, Reeta R. Singhania, Ashok Pandey and Christian Larroche
Elsevier LTD. Pp. 169-200. ISBN: 978-0-444-64114-4

PUBLICACIONES 2018

Nanotechnology and Drug Delivery

Islan G.A., Martin-Saldaña S., Chevalier M.T., Alvarez V.A., Castro G.R. (2018) Nanotechnology and Drug Delivery. In: Talevi A., Quiroga P. (eds) ADME Processes in Pharmaceutical Sciences. Springer, Cham, pages: 135-165

  • Print ISBN978-3-319-99592-2   
  • Online ISBN978-3-319-99593-9

Self-Assembly Stereo-Specific Synthesis of Silver Phosphate Microparticles on Bacterial Cellulose Membrane Surface For Antimicrobial Applications

Bernardo Bayón, Maximiliano L.Cacicedo, Vera A.Álvarez, Guillermo R.Castro…
Colloid and Interface Science Communications:  Volume 26, September 2018, Pages 7-13

Bacterial Cellulose Hydrogel Loaded with Lipid Nanoparticles for Localized Cancer Treatment

ML Cacicedo, GA Islan, IE León, VA Álvarez, I Chourpa, E Allard-Vannier, …
Colloids and Surfaces B: Biointerfaces 170, 596-608

 
 

Simple colorimetric method to determine the in vitro antioxidant activity of different monoterpenes

N Noacco, B Rodenak-Kladniew, MG de Bravo, GR Castro, GA Islan
Analytical biochemistry 55, 59-66

 
 

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: physicochemical characterization and in vitro/in vivo evaluation

SS Montoto, ML Sbaraglini, A Talevi, M Couyoupetrou, M Di Ianni, …
Colloids and Surfaces B: Biointerfaces 167, 73-81
 
 

Optimization of culture conditions for kefiran production in whey: The structural and biocidal properties of the resulting polysaccharide

LM Blandón, MD Noseda, GA Islan, GR Castro, GV de Melo Pereira, …
Bioactive Carbohydrates and Dietary Fibre
 
 

Hybrid bacterial cellulose-pectin films for delivery of bioactive molecules

ML Cacicedo, GA Islan, MF Drachemberg, VA Alvarez, L Bartel, …
New Journal of Chemistry 42, 7457-7467
 
 

Biopolymers from Wastes to High-Value Products in Biomedicine

B Bayón, IR Berti, AM Gagneten, GR Castro
Waste to Wealth, 1-44
 
 

PUBLICACIONES 2017

Development and tailoring of hybrid lipid nanocarriers

GA Islan, ML Cacicedo, B Rodenak-Kladniew, N Duran, GR Castro
Current pharmaceutical design 23 (43), 6643-6658
 
 

An introduction to Pharmacokinetics from conventional to advanced drug delivery systems

A Talevi, LB Blanch, GR Castro
Drug Delivery: An Integrated Clinical and Engineering Approach, 13-46
 

Drug delivery devices for infectious diseases

 
ML Cacicedo, GA Islan, P Gurman, GR Castro
Drug delivery: an integrated clinical and engineering approach., 347-370
 
 

Interaction of Solid Lipid Nanoparticles and specific proteins of the corona studied by Surface Plasmon Resonance

 
M Di ianni, GA Islan, CY Chain, GR Castro, A Talevi, ME Vela
Journal of Nanomaterials 2017 (Article ID 6509184), 1-11
 
 

Novel cheese production by incorporation of sea buckthorn berries (Hippophae rhamnoides L.) supported probiotic cells

A Terpou, AI Gialleli, L Bosnea, M Kanellaki, AA Koutinas, GR Castro
LWT-Food Science and Technology 79, 616-624
 
 

Cellulose-Containing Scaffolds Fabricated by Electrospinning: Applications in Tissue Engineering and Drug Delivery

 
A López-Córdoba, GR Castro, S Goyanes
Handbook of Composites from Renewable Materials, Nanocomposites: Advanced …
 
 

Design, characterization and in vitro evaluation of linalool-loaded solid lipid nanoparticles as potent tool in cancer therapy

 
B Rodenak-Kladniew, GA Islan, MG de Bravo, N Durán, GR Castro
Colloids and Surfaces B: Biointerfaces 154, 123-132
 
 

Hybrid inhalable microparticles for dual controlled release of levofloxacin and DNase: Physicochemical characterization and in-vivo targeted delivery to the lungs

 
GA Islan, ME Ruiz, JF Morales, AV Sbaraglini, Maria L., Enrique, G Burton, …
Journal of Material Chemistry B 5, 3132-3144
 
 

Nanopharmaceuticals as a solution to neglected diseases: Is it possible?

 
GA Islan, M Durán, ML Cacicedo, G Nakazato, RKT Kobayashi, …
Acta Tropica 170, 16-42
 
 

Desarrollo de bioimpresora 3D con 4to eje rotativo para uso en biotecnología, farmacología e ingeniería de tejidos

 
S Katz, B Bayón, GR Castro
I Workshop de Ciencia Abierta y Ciudadana-Argentina (La Plata, 2017)
 
 

Silver Nanoparticles for Treatment of Neglected Diseases

 
M Durán, WJ Fávaro, GA Islan, GR Castro, N Durán
Metal Nanoparticles in Pharma, 39-51
 
 

Emerging Technologies for Bioactive Applications in Foods

 
LG Santiago, CR Soccol, GR Castro
Food Bioactives, 205-226
 
 

Targeted Therapies (Editorial)

 
A Talevi, GR Castro
Mini-Reviews in Medicinal Chemistry 17 (3), 186-187

PUBLICACIONES 2016

Kefiran-alginate gel microspheres for oral delivery of ciprofloxacin, Colloids and Surfaces B: Biointerfaces

Lina M. Blandón, German A. Islan, Guillermo R. Castro, Miguel D. Noseda, Vanete Thomaz-Soccol, Carlos R. Soccol,
Volume 145, 2016, Pages 706-715,
ISSN 0927-7765

Development of Crystal Violet encapsulation in pectin – Arabic gum gel microspheres,Reactive and Functional Polymers

Mariana V. Revuelta, M. Elizabeth Chacon Villalba, Alba S. Navarro, Jorge A. Güida, Guillermo R. Castro.
Volume 106, 2016, Pages 8-16,
ISSN 1381-5148

A simple green route to obtain poly(vinyl alcohol) electrospun mats with improved water stability for use as potential carriers of drugs,
Materials Science and Engineering: C

Alex López-Córdoba, Guillermo R. Castro, Silvia Goyanes
Volume 69, 2016, Pages 726-732,
ISSN 0928-4931

Progress in bacterial cellulose matrices for biotechnological applications, Bioresource Technology.

Maximiliano L. Cacicedo, M. Cristina Castro, Ioannis Servetas, Loulouda Bosnea, Konstantina Boura, Panagiota Tsafrakidou, Agapi Dima, Antonia Terpou, Athanasios Koutinas, Guillermo R. Castro.
Volume 213, 2016, Pages 172-180,
ISSN 0960-8524

Preparation And Characterization Of Polyvinyl Alcohol–pectin Cryogels Containing Enrofloxacin And Keratinase As Potential Transdermal Delivery Device

Guillermo R. Castro.
Volume 7, issue 8, 2016, Pages 640-645,

 

Smart lipid nanoparticles containing levofloxacin and DNase for lung delivery. Design and characterization

Germán A. Islan, Pablo Cortez Tornello, Gustavo A. Abraham, Nelson Duran, Guillermo R. Castro.
Volume 143, 2016, Pages 168-176.
ISSN 0927-7765

Advances in Chromobacterium violaceum and properties of violacein-Its main secondary metabolite: A review

Durán N, Justo GZ, Durán M, Brocchi M, Cordi L, Tasic L, Castro GR, Nakazato G.
Biotechnol Adv. 2016 Sep-Oct;34(5) 1030-1045.
doi:10.1016/j.biotechadv.2016.06.003. PMID: 27288924.

Development of antimicrobial hybrid mesoporous silver phosphate–pectin microspheres for control release of levofloxacin

Bernardo Bayón, Verónica Bucalá, Guillermo R. Castro,

Volume 226, 2016, Pages 71-78,

ISSN 1387-1811.

 

Modified bacterial cellulose scaffolds for localized doxorubicin release in human colorectal HT-29 cells

Maximiliano L. Cacicedo, Ignacio E. León, Jimena S. Gonzalez, Luismar M. Porto, Vera A. Alvarez, Guillermo R. Castro,

Volume 140, 1 April 2016, Pages 421-429

ISSN 0927-7765

 

Novel technologies for the encapsulation of bioactive food compounds

Liliana G. Santiago,  Guillermo R. Castro

Volume 7, 2016, Pages 78-85.

ISSN 2214-7993

Nanodevices for the immobilization of therapeutic enzymes

Valeria E. Bosio, Germán A. Islan, Yanina N. Martínez, Nelson Durán  & Guillermo R. Castro

Pages 447-464

ISSN 2214-7993

Construction and in vitro testing of a cellulose dura mater graft

Ezequiel Goldschmidt, Maximiliano Cacicedo, Sebastián Kornfeld, Marina Valinoti, Marcelo Ielpi, Pablo M. Ajler, Claudio Yampolsky, Jorge Rasmussen, Guillermo R. Castro & Pablo Argibay

Volume 38, 2016 – Issue 1

Advances in Chromobacterium violaceum and properties of violacein-Its main secondary metabolite: A review

Nelson Durán, Giselle Z. Justo, Marcela Durán, Marcelo Brocchi, Livia Cordi, Ljubica Tasic, Guillermo R. Castro, Gerson Nakazato.

Volume 34, Issue 5, 2016, Pages 1030-1045.
ISSN 0734-9750

A simple green route to obtain poly(vinyl alcohol) electrospun mats with improved water stability for use as potential carriers of drugs

Alex López-Córdoba, Guillermo R. Castro, Silvia Goyanes

Volume 69, 2016, Pages 726-732,
ISSN 0928-4931

PUBLICACIONES 2015

Characterization of smart auto-degradative hydrogel matrix containing alginate lyase to enhance levofloxacin delivery against bacterial biofilms

German A. Islan, Cecilia Dini, Laura C. Bartel, Alejandro D. Bolzán, Guillermo R. Castro,

International Journal of Pharmaceutics,
Volume 496, Issue 2, 2015, Pages 953-964
ISSN 0378-5173

Self-assembly of carrageenin–CaCO3 hybrid microparticles on bacterial cellulose films for doxorubicin sustained delivery

Maximiliano L. Cacicedo, Karina Cesca, Valeria E. Bosio, Luismar M. Porto, Guillermo R. Castro,

Journal of Applied Biomedicine, Volume 13, Issue 3, 2015, Pages 239-248,
ISSN 1214-021x

Development of biopolymer nanocomposite for silver nanoparticles and Ciprofloxacin controlled release

German A.Islan, ArupMukherjee, Guillermo R.Castro

International Journal of Biological Macromolecules, Volume 72, 2015, Pages 740-750,
ISSN 0141-8130

Milk kefir: composition, microbial cultures, biological activities, and related products

Maria R. Prado, Lina Marcela Blandón, Luciana P. S. Vandenberghe, Cristine Rodrigues,
Guillermo R. Castro, Vanete Thomaz-Soccol and Carlos R. Soccol.

Frontier in Microbiology, 2015, Pages 22-41

Development and characterization of new enzymatic modified hybrid calcium carbonate microparticles to obtain nano-architectured surfaces for enhanced drug loading

G.A. Islan, M.L. Cacicedo, V.E. Bosio, G.R. Castro.

Journal of Colloid and Interface Science, Volume 439, 2015, Pages 76-87.
ISSN 0021-9797

Industrial Biorefineries & White Biotechnology

Licia M. Pera, Mario D. Baigori, Ashok Pandey and Guillermo R. Castro

Chapter 10 – Biocatalysis, In Industrial Biorefineries & White Biotechnology, Elsevier, Amsterdam, 2015, Pages 391-408.

ISBN 9780444634535