PUBLICACIONES 2023

• Rodenak-Kladniew, B., Gambaro, R., Cisneros, J. S., Huck-Iriart, C., Padula, G., Castro, G. R., … & Islan, G. A. (2023). Enhanced anticancer activity of encapsulated geraniol into biocompatible lipid nanoparticles against A549 human lung cancer cells. Journal of Drug Delivery Science and Technology, 80, 104159.
  
  
• Boztepe, T., Scioli-Montoto, S., Gambaro, R. C., Ruiz, M. E., Cabrera, S., Alemán, J., Islan, G. A., … & León, I. E. (2023). Design, Synthesis, Characterization, and Evaluation of the Anti-HT-29 Colorectal Cell Line Activity of Novel 8-Oxyquinolinate-Platinum (II)-Loaded Nanostructured Lipid Carriers Targeted with Riboflavin. Pharmaceutics, 15(3), 1021.
  
  
• Muraca, G., Ruiz, M. E., Gambaro, R. C., Scioli-Montoto, S., Sbaraglini, M. L., Padula, G., … Islan, G.A. & Talevi, A. (2023). Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies. Beilstein Journal of Nanotechnology, 14(1), 804-818.
  
  
• Rodenak-Kladniew, B., Castro, M. A., Gambaro, R. C., Girotti, J., Cisneros, J. S., Viña, S., … & Islan, G. A. (2023). Cytotoxic screening and enhanced anticancer activity of Lippia alba and Clinopodium nepeta essential oils-loaded biocompatible lipid nanoparticles against lung and colon cancer cells. Pharmaceutics, 15(8), 2045.
  
  
• Buldain, D., Mestorino, N., & Islan, G. (2023). Nanobiotecnología como alternativa para el tratamiento de mastitis bovina por Staphylococcus aureus: nanopartículas conteniendo aceite esencial de Melaleuca armillaris Sm. y cloxacilina. Investigación Joven, 10(3), 420-421.
  
  
• Berti, I. R., Gantner, M. E., Rodriguez, S., Islan, G. A., Fávaro, W. J., Talevi, A., … & Durán, N. (2023). Potential biocide roles of violacein. Nanotechnology and nanoscience to manage SARS-CoV-2 variants of concern, 213.

 

PUBLICACIONES 2022

• Aleixo, N. A., Gomes, P. S. D. S., Silva, P. B. D., Sato, M. R., Campos, D. L., Barud, H. D. S., Castro, G. R., Islan, G. A., … & Resende, F. A. (2022). Study of antimycobacterial, cytotoxic, and mutagenic potential of polymeric nanoparticles of copper (II) complex. Journal of Microencapsulation, 39(1), 61-71.
  
  
• Islan, G. A., Rodenak-Kladniew, B., Noacco, N., Duran, N., & Castro, G. R. (2022). Prodigiosin: a promising biomolecule with many potential biomedical applications. Bioengineered, 13(6), 14227-14258.
  
  
• Medina-Montano, C., Rivero Berti, I., Gambaro, R. C., Limeres, M. J., Svensson, M., Padula, G., … Islan, G. A. & Cacicedo, M. L. (2022). Nanostructured Lipid Carriers Loaded with Dexamethasone Prevent Inflammatory Responses in Primary Non-Parenchymal Liver Cells. Pharmaceutics, 14(8), 1611.
  
  
• Scioli-Montoto, S., Sbaraglini, M. L., Cisneros, J. S., Chain, C. Y., Ferretti, V., León, I. E., Alvarez, V. A., Castro, G. R., Islan, G. A., Talevi, A. & Ruiz, M. E. (2022). Novel Phenobarbital-Loaded Nanostructured Lipid Carriers for Epilepsy Treatment: From QbD to In Vivo Evaluation. Frontiers in Chemistry, 10, 908386.
  
  
• Rosli, N. A., Islan, G. A., Hasham, R., Castro, G. R., & Aziz, A. A. (2022). Incorporation of Nanoparticles Based on Zingiber Officinale Essential Oil into Alginate Films for Sustained Release. Journal of Physical Science, 33(2).
  
  
• Gambaro, R. C., Berti, I. R., Cacicedo, M. L., Gehring, S., Alvarez, V. A., Castro, G. R., … & Islan, G. A. (2022). Colloidal delivery of vitamin E into solid lipid nanoparticles as a potential complement for the adverse effects of anemia treatment. Chemistry and Physics of Lipids, 249, 105252.
  
  

PUBLICACIONES 2021

• Islan, G. A., Gonçalves, L. M., Marto, J., Duarte, A., Alvarez, V. A., Castro, G. R., & Almeida, A. J. (2021). Effect of α-tocopherol on the physicochemical, antioxidant and antibacterial properties of levofloxacin loaded hybrid lipid nanocarriers. New Journal of Chemistry, 45(2), 1029-1042.
  
• Toledo, C., Gambaro, R. C., Padula, G., Vela, M. E., Castro, G. R., Chain, C. Y., & Islan, G. A. (2021). Binary medical nanofluids by combination of polymeric Eudragit nanoparticles for vehiculization of tobramycin and resveratrol: Antimicrobial, hemotoxicity and protein corona studies. Journal of pharmaceutical sciences, 110(4), 1739-1748.
  
  
• Karp, F., Turino, L. N., Helbling, I. M., Islan, G. A., Luna, J. A., & Estenoz, D. A. (2021). In situ Formed Implants, Based on PLGA and Eudragit Blends, for Novel Florfenicol Controlled Release Formulations. Journal of Pharmaceutical Sciences, 110(3), 1270-1278.
  
  
• Montoto, S. S., Muraca, G., Di Ianni, M., Couyoupetrou, M., Pesce, G., Islan, G. A., … & Castro, G. R. (2021). Preparation, physicochemical and biopharmaceutical characterization of oxcarbazepine-loaded nanostructured lipid carriers as potential antiepileptic devices. Journal of Drug Delivery Science and Technology, 63, 102470.
  
  
• Rodenak-Kladniew, B., Noacco, N., de Berti, I. P., Stewart, S. J., Cabrera, A. F., Alvarez, V. A., … & Islan, G. A. (2021). Design of magnetic hybrid nanostructured lipid carriers containing 1, 8-cineole as delivery systems for anticancer drugs: Physicochemical and cytotoxic studies. Colloids and Surfaces B: Biointerfaces, 202, 111710.
  
  
• Muraca, G. S., Soler-Arango, J., Castro, G. R., Islan, G. A., & Brelles-Mariño, G. (2021). Improving ciprofloxacin antimicrobial activity through lipid nanoencapsulation or non-thermal plasma on Pseudomonas aeruginosa biofilms. Journal of Drug Delivery Science and Technology, 102644.
  
  
• Berti, I. R., Islan, G. A., & Castro, G. R. (2021). Enzymes and biopolymers. The opportunity for the smart design of molecular delivery systems. Bioresource Technology, 124546.

 

Preparation, physicochemical and biopharmaceutical characterization of oxcarbazepine-loaded nanostructured lipid carriers as potential antiepileptic devices

S.Scioli Montoto^a G.Muraca^ab M.Di Ianni^a M.Couyoupetrou^ab G.Pesce^b G.A.Islan^c C.Y.Chain^d M.E.Vela^d M.E.Ruiz^a A.Talevi^a G.R.Castro^ce

^aLaboratorio de Investigación y Desarrollo de Bioactivos (LIDeB), Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP), Calle 47 y 115 (B1900AJI), La Plata, Buenos Aires, Argentina
^bDepartamento de Farmacología, Instituto Nacional de Medicamentos (INAME), Administración Nacional de Medicamentos, Alimentos y Tecnología Médica (ANMAT), CABA, Buenos Aires, Argentina
^cLaboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP) -CONICET (CCT La Plata), Calle 47 y 115, (B1900AJI), La Plata, Buenos Aires, Argentina
^dInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), CONICET-UNLP, CC 16 Suc 4, La Plata, 1900, Buenos Aires, Argentina
^eMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC). Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG). Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000, Rosario, Santa Fe, Argentina

Received 24 November 2020, Revised 23 February 2021, Accepted 3 March 2021, Available online 6 March 2021.
https://doi.org/10.1016/j.jddst.2021.102470

Editorial: Lipid Nanoparticles as a Novel Strategy to Deliver Bioactive Molecules

Alan Talevi^1,2*, Nelson Duran³ and Guillermo Raul Castro¹

• ¹Laboratory of Bioactive Research and Development (LIDeB), Department of Biological Sciences, Faculty of Exact Sciences, University of La Plata (UNLP), La Plata, Argentina
• ²Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina
• ³Laboratory of Urogenital Carcinogenesis andImmunotherapy, Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil
• ⁴Laboratorio de Nanobiomateriales, Centro de Investigacióny Desarrollo enFermentaciones Industriales (CINDEFI), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional deLa Plata (UNLP)-CONICET (CCT La Plata), La Plata, Argentina

Front. Chem., 04 March 2021
https://doi.org/10.3389/fchem.2021.655480

Design of magnetic hybrid nanostructured lipid carriers containing 1,8-cineole as delivery systems for anticancer drugs: Physicochemical and cytotoxic studies

B.Rodenak-Kladniew^a N.Noacco^b I.Pérez de Berti^c S.J.Stewart^d A.F.Cabrera^d V.A.Alvarez^e M.García de Bravo^a N.Durán^fg G.R.Castro^bh G.A.Islan^b

^aInstituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), CONICET-UNLP, CCT-La Plata, Facultad de Ciencias Médicas, La Plata, Argentina
^bLaboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP) -CONICET (CCT La Plata), Calle 47 y 115, B1900AJI, La Plata, Buenos Aires, Argentina
^cCINDECA, CONICET-CICPBA-Universidad Nacional de La Plata, Facultad de Ciencias Exactas, Calle 47 N 257, 1900, La Plata, Argentina
^dIFLP-CONICET, Departamento de Física, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, C. C. 67, 1900, La Plata, Argentina
^eGrupo de Materiales Compuestos Termoplásticos (CoMP), Instituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA), Facultad de Ingeniería, Universidad Nacional de Mar del Plata (UNMdP) y Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Av. Colón 10850, 7600, Mar del Plata, Argentina
^fLaboratory of Urogenital Carcinogenesis and Immunotherapy, Department of Structural and Functional Biology, Biology Institute, University of Campinas, Campinas, SP, Brazil
^gNanomedicine Research Unit (Nanomed), Federal University of ABC (UFABC), Santo André, SP, Brazil
^hMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC). Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG). Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000, Rosario, Santa Fe, Argentina

Received 1 July 2020, Revised 9 February 2021, Accepted 16 March 2021, Available online 19 March 2021.
https://doi.org/10.1016/j.colsurfb.2021.111710

 

 

Improving ciprofloxacin antimicrobial activity through lipid nanoencapsulation or non-thermal plasma on Pseudomonas aeruginosa biofilms

Giuliana S.Muraca^a JulianaSoler-Arango^a Guillermo R.Castro^bc Germán A.Islan^b GracielaBrelles-Mariño^a

^aBiofilm Eradication Laboratory. Centro de Investigación y Desarrollo en Fermentaciones Industriales, Consejo Nacional de Investigaciones Científicas y Técnicas (CINDEFI, CCT-LA PLATA-CONICET), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina^bLaboratorio de Nanobiomateriales – CINDEFI (CCT-LA PLATA-CONICET), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina^cMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC). Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG). Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000 Rosario, Santa Fe, Argentina

Received 29 October 2020, Revised 26 May 2021, Accepted 29 May 2021, Available online 9 June 2021.
https://doi.org/10.1016/j.jddst.2021.102644

 

Lipid, polymeric, inorganic-based drug delivery applications for platinum-based anticancer drugs

TugceBoztepe^aGuillermo R.Castro^abIgnacio E.León^c

^aLaboratorio de Nanobiomateriales, CINDEFI – Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata-CONICET (CCT La Plata), Calle 47 y 115, B1900AJL La Plata, Argentina^bMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC), Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG), Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000 Rosario, Santa Fe, Argentina^cCentro de Química Inorgánica, CEQUINOR (CONICET-UNLP), Bv. 120 1465, La Plata, Argentina

Received 15 December 2020, Revised 2 June 2021, Accepted 5 June 2021, Available online 9 June 2021.
https://doi.org/10.1016/j.ijpharm.2021.120788

Patents on Violacein: A Compound with Great Diversity of Biological Activities and Industrial Potential

Nelson Durán ¹, Wagner J Fávaro ¹, Marcelo Brocchi ², Giselle Z Justo ³, Guillermo R Castro ⁴, Marcela Durán ¹, Gerson Nakazato ⁵

• ¹Laboratory of Urogenital Carcinogenesis and Immunotherapy, Biology Institute, Department of Structural and Functional Biology, University of Campinas,Campinas, SP. Brazil.
• ²Laboratory of Tropical Diseases, Institute of Biology, Department of Genetic, Evolution, Microbiology and Immunology. University of Campinas, Campinas, SP. Brazil.
• ³Department of Pharmaceutical Sciences and Department of Biochemistry, Federal University of São Paulo (UNIFESP). Brazil.
• ⁴Nanobiomaterials Laboratory, Institute of Applied Biotechnology CINDEFI (UNLP-CONICET, CCT La Plata), Department of Chemistry, School of Sciences, Universidad Nacional de La Plata, La Plata. Argentina.
• ⁵Laboratory of Basic and Applied Bacteriology, Department of Microbiology, Biology Sciences Center, Londrina State University (UEL), Londrina. Brazil.

PMID: 33349223 DOI: 10.2174/2213476X07666201221111655

Isolation and partial characterization of Komagataeibacter sp. SU12 and optimization of bacterial cellulose production using Mangifera indica extracts

Calderón-Toledo S., Horue M., Alvarez V.A., Castro G.R., Zavaleta A.I. (2021)
Journal of Chemical Technology and Biotechnology. 
In press. DOI: 10.1002/jctb.6839. (ISSN: 0268-2575). IF: 3.174.

Multi-target drug with potential applications: A spot on violacein

Durán N., Nakazato G., Durán M., Rivero Berti I., Castro G.R., Stanisic D., Brocchi M., Fávaro W.J., Ferreira-Halder C.V., Zenker Justo G., Tasic L. 
2021
World Journal of Microbiology and Biotechnology. Accepted. (ISSN: 0959-3993). IF:2.477.

Microbial production and recovery of hybrid biopolymers from wastes for industrial applications- a review

Laboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP) -CONICET (CCT La Plata), Calle 47 y 115, (B1900AJI), La Plata, Buenos Aires, Argentina^bChildren’s Hospital, University Medical Center, Johannes Gutenberg-University, Mainz, Germany^cMax Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR, UNR-MPIbpC). Partner Laboratory of the Max Planck Institute for Biophysical Chemistry (MPIbpC, MPG). Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000 Rosario, Santa Fe, Argentina

Received 31 May 2021, Revised 23 July 2021, Accepted 24 July 2021, Available online 27 July 2021.

https://doi.org/10.1016/j.biortech.2021.125671

Bioresource Technology
Volume 340, November 2021, 125671

Ecotoxicologic effects of silver nanoparticles on freshwater nontarget species

Natalı´ Romero1,2, Guillermo R. Castro2,3,4, Ana Marı´a Gagneten1
1Laboratorio de Ecotoxicologia, Departamento de Ciencias Naturales, Facutad de Humanidades y
Ciencias, Universidad Nacional del Litoral, (FHUC, UNL), Santa Fe, Argentina; 2Consejo Nacional
de Investigaciones Cientı´ficas y Te´cnicas (CONICET), Argentina; 3Laboratorio de
Nanobiomateriales, CINDEFI e Depto. de Quı´mica, Facultad de Ciencias Exactas, Universidad de
La Plata e CONICET (CCT La Plata), La Plata, Buenos Aires, Argentina; 4Max Planck
Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario (MPLbioR,
UNR-MPIbpC), Partner Laboratory of the Max Planck Institute for Biophysical Chemistry
(MPIbpC, MPG), Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario,
Maipu´, Rosario, Santa Fe, Argentina

ISBN: 978-0-12-822965-1

New Trends in Removal of Heavy Metals from Industrial Wastewater
Chapter 28

Copyright © 2021 Elsevier Inc.

 

Simultaneous electrochemical detection of ciprofloxacin and Ag(I) in a
silver nanoparticle dissolution: Application to ecotoxicological
acute studies

Silvina V. Kergaravat a,b,*, Natalí Romero a, Luciana Regaldo a, Guillermo R. Castro c,d, Silvia
R. Hernández b, Ana María Gagneten a

a Laboratorio de Ecotoxicología, Facultad de Humanidades y Ciencias, Universidad Nacional del Litoral (UNL), UNL-CONICET, CCT Santa Fe, 3000 Santa Fe, Argentina
b Laboratorio de Sensores y Biosensores, Facultad de Bioquímica y Ciencias Biológicas, UNL-CONICET, CCT Santa Fe, 3000 Santa Fe, Argentina
c Laboratorio de Nanobiomateriales, CINDEFI – Facultad de Ciencias Exactas (UNLP – CONICET, CCT La Plata), La Plata 1900, Argentina
d Laboratorio Max Planck de Biología Estructural, Química y Biofísica Molecular de Rosario (MPLbioR, UNR-MPIbpC), Laboratorio Asociado del Instituto Max Planck
para Química Biofísica (MPIbpC, MPG), Centro de Estudios Interdisciplinarios (CEI), Universidad Nacional de Rosario, Maipú 1065, S2000 Rosario, Santa Fe, Argentina

* Corresponding author: E-mail address: skergaravat@fbcb.unl.edu.ar (S.V. Kergaravat).

https://doi.org/10.1016/j.microc.2020.105832

Received 29 June 2020; Received in revised form 29 October 2020; Accepted 20 November 2020, Available online 11 December 2020

0026-265X/© 2020 Elsevier B.V.

 

Physiological and morphological responses of green microalgae Chlorella
vulgaris to silver nanoparticles

Natalí Romero a,b, Flavia F. Visentini b,d, Vanina E. Máarquez e, Liliana G. Santiago b,d,
Guillermo R. Castro c, Ana M. Gagneten a,*

a Laboratorio de Ecotoxicología, Facultad de Humanidades y Ciencias, Universidad Nacional del Litoral, Ciudad Universitaria – Paraje El Pozo S/n (3000), Santa Fe,
Argentina
b CONICET, Predio CONICET “Dr. Alberto Cassano”, Colectora Ruta Nac. Nº 168, Km. 0, Paraje El Pozo (3000), Santa Fe, Argentina
c Laboratorio de Nanobiomateriales, CINDEFI – Departamento de Química – Facultad de Ciencias Exactas, Universidad Nacional de La Plata – CONICET (CCT La Plata),
Calle 50 Nº 227, La Plata, 1900, Buenos Aires, Argentina
d Area de Biocoloides y Nanotecnología, Instituto de Tecnología de Alimentos (ITA), Facultad de Ingeniería Química (FIQ), Universidad Nacional del Litoral (UNL),
Santiago Del Estero 2829, Santa Fe, Argentina
e Laboratorio de Fermentaciones, Facultad de Bioquímica y Ciencias Biolóogicas, Universidad Nacional del Litoral, Ciudad Universitaria – Paraje El Pozo S/n (3000),
Santa Fe, Argentina
* Corresponding author: E-mail address: amgagneten@fhuc.unl.edu.ar (A.M. Gagneten).

https://doi.org/10.1016/j.envres.2020.109857
Received 15 April 2020; Received in revised form 29 May 2020; Accepted 12 June 2020, Available online 11 July 2020
0013-9351/© 2020 Elsevier Inc.

 

Silver nanoparticle flter for domestic wastewater reuse

Ana M Gagneten, a* Natalí Romero,a,b Ulises Reno,a,b Luciana Regaldo,a,b
Silvina V Kergaravat,a,b,c Boris E Rodenak-Kladniewd and
Guillermo R Castroe,f*

a Laboratorio de Ecotoxicología, Facultad de Humanidades y Ciencias, Universidad
Nacional del Litoral, Santa Fe, Argentina
b Consejo Nacional de Investigaciones Cientícas y Técnicas (CONICET), Santa
Fe, Argentina
c Laboratorio de Sensores y Biosensores, Facultad de Bioquímica y Ciencias Biológicas,
Universidad Nacional del Litoral, Santa Fe, Argentina
d Facultad de Ciencias Médicas, Instituto de Investigaciones Bioquímicas de La
Plata (INIBIOLP), CONICET-UNLP, CCT-La Plata, La Plata, Argentina
e Laboratorio de Nanobiomateriales, CINDEFI, Departamento de Química,
Facultad de Ciencias Exactas, Universidad Nacional de La Plata – CONICET
(CCT La Plata), Buenos Aires, Argentina
f Max Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics
of Rosa rio (MPLbioR, UNR-MPIbpC), Partner Laboratory of the Max
Planck Institute for Biophysical Chemistry (MPIbpC, MPG), Centro de Estudios
Interdisciplinarios (CEI), Universidad Nacional de Rosario, Rosario, Argentina

Received: 23 December 2020 Revised: 25 February 2021 Accepted article published: 2 March 2021 Published online in Wiley Online Library

DOI 10.1002/jctb.6710

https://onlinelibrary.wiley.com/

PUBLICACIONES 2020

Physiological and morphological responses of green microalgae Chlorella vulgaris to silver nanoparticles

Natalí Romero (a)(b), Flavia F. Visentini (b)(d), Vanina E. Márquez (e),Liliana G. Santiago (b)(d), Guillermo R. Castro (c) ,Ana M. Gagneten (a)

(a) Laboratorio de Ecotoxicología, Facultad de Humanidades y Ciencias, Universidad Nacional del Litoral, Ciudad Universitaria – Paraje El Pozo S/n (3000), Santa Fe, Argentina
(b) CONICET, Predio CONICET “Dr. Alberto Cassano”, Colectora Ruta Nac. Nº 168, Km. 0, Paraje El Pozo (3000), Santa Fe, Argentina
(c) Laboratorio de Nanobiomateriales, CINDEFI – Departamento de Química – Facultad de Ciencias Exactas, Universidad Nacional de La Plata – CONICET (CCT La Plata), Calle 50 Nº 227, La Plata, 1900, Buenos Aires, Argentina
(d) Área de Biocoloides y Nanotecnología, Instituto de Tecnología de Alimentos (ITA), Facultad de Ingeniería Química (FIQ), Universidad Nacional del Litoral (UNL), Santiago Del Estero 2829, Santa Fe, Argentina
(e) Laboratorio de Fermentaciones, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Ciudad Universitaria – Paraje El Pozo S/n (3000), Santa Fe, Argentina

Received 15 April 2020, Revised 29 May 2020, Accepted 12 June 2020, Available online 11 July 2020.

DOI: https://doi.org/10.1016/j.envres.2020.109857

Environmental Research, Volume 189, October 2020, 109857

 

Assessment of in vitro cytotoxicity of imidazole ionic liquids and inclusion in targeted drug carriers containing violacein

Ignacio Rivero Berti (a), Boris Rodenak-Kladniew (b), Celeste Onaindia (c), Claudia G. Adam (c), German A. Islan (a), Nelson Durán (d e) and Guillermo R. Castro (a)

(a) Laboratorio de Nanobiomateriales, CINDEFI, Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata-CONICET (CCT La Plata), Calle 47 y 115, B1900AJL La Plata, Argentina
E-mail: grcastro@gmail.com
(b) Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), CONICET-UNLP, CCT-La Plata, Facultad de Ciencias Médicas, B1900 La Plata, Argentina
(c) IQAL, Instituto de Química del Litoral (UNL-CONICET), Facultad de Ingeniería Química-Universidad Nacional del Litoral, Santiago del Estero 2829, Santa Fe, Argentina
(d) Institute of Biology, Universidade Estadual de Campinas, C.P. 6159, Campinas, SP, Brazil
(e) NanoMed Center, Federal University of ABC (UFABC), Santo André, SP, Brazil
DOI: http://xlink.rsc.org/?DOI=d0ra05101b
Issue 49, 2020

Design of nalidixic acid‑vanadium complex loaded into chitosan hybrid nanoparticles as smart strategy to inhibit bacterial growth and quorum sensing