Bio-inks for 3D extrusion-based bio-printed scaffolds: Printability

Verónica E. Passamai (a), ; Sergio Katz (a), Vera Alvarez (b), Guillermo R. Castro (a)*
(a) Nanobiomaterials Lab, CINDEFI, School of Sciences, National University of La Plata-CONICET (CCT La Plata), Buenos Aires, Argentina
(b) Grupo de Materiales Compuestos Termoplásticos (CoMP), Instituto de Investigaciones en Ciencia y Tecnología de Materiales (INTEMA), Facultad de Ingeniería, Universidad Nacional de Mar del Plata (UNMDP) – CONICET, Av. Colón 10850 (B7608FDQ), Mar del Plata, Buenos Aires,


Volume 2, N 1, March-September, pag. 43 -45

Development and characterization of an improved formulation of cholesteryl oleate-loaded cationic solid-lipid nanoparticles as an efficient non-viral gene delivery system

María J. Limeres (a,b,c) , Marc Suñé-Poua (b)⁎⁎, Silvia Prieto-Sánchez (b), Cristina Moreno-Castro(b),
Alejandro D. Nusblat(d), Cristina Hernández-Munain(e), Guillermo R. Castro(f), Carlos Suñé(b),
Josep M. Suñé-Negre(a), María L. Cuetsas (c,⁎)
a Service of Development of Medicines (SDM), Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
b Department of Molecular Biology, Institute of Parasitology and Biomedicine “López-Neyra” (IPBLN-CSIC), Granada, Spain
c Institute of Research in Microbiology and Medical Parasitology (IMPaM), Faculty of Medicine, University of Buenos Aires-CONICET, Buenos Aires, Argentina
d Institute of Nanobiotechnology (NANOBIOTEC), Faculty of Pharmacy and Biochemistry, University of Buenos Aires-CONICET, Buenos Aires, Argentina
e Department of Cell Biology and Immunology, Institute of Parasitology and Biomedicine “López-Neyra” (IPBLN-CSIC), Granada, Spain
f Nanobiomaterials Lab, CINDEFI, School of Sciences, National University of La Plata-CONICET (CCT La Plata), Buenos Aires, Argentina

Colloids and Surfaces B: Biointerfaces
Volume 184, 1 December 2019, 110533


Lipid nanoparticles – Metvan: revealing a novel way to deliver a vanadium compound to bone cancer cells


M. L. Cacicedo, M. C. Ruiz, S. Scioli-Montoto, M. E. Ruiz, M. A. Fernández, R. M. Torres-Sanchez, E. J. Baran, G. R. Castro and I. E. León
New Journal of Chemistry
July 2019

Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties

B.Rodenak-Kladniew, S.Scioli Montotob, M.L.Sbaraglini, M.Di Ianni, M.E.Ruiz, A.Talevi, V.A.Alvarez, N.Duránd, G.R.Castro, G.A.Islan
International Journal of Pharmaceutics
Volume 569, July 2019

Silybin-conjugated gold nanoparticles for antimicrobial chemotherapy against Gram-negative bacteria

German A.Islan,  Suvadra Das, Maximiliano L.Cacicedo,  Asim Halder, Asmita Mukherjee, María Luján Cuestas, Partha Roy , Guillermo R.Castro, Arup Mukherjeed
Journal of Drug Delivery Science and Technology
Volume 53, July2019

Formation and characterization of self-assembled bovine serum albumin nanoparticles as chrysin delivery systems

Ferrado J.B., Perez A.A., Visentini F.V., Islan G.A., Castro G.R., Santiago L
Colloids and Surfaces B: Biointerfaces
Volume 173, 1 January 2019, Pages 43-51

A new glioblastoma cell trap for implantation after surgical resection

Autier L., Clavreul A., Cacicedo M.L., Franconi F., Sindji L., Rousseau A., Perrot R., Montero-Menei C.N., Castro G.R., Menei P
Acta Biomaterialia
Volume 84, 15 January 2019, Pages 268-279

Development of biocarrier for violacein controlled release in the treatment of cancer

Rivero Berti I., Rodenak-Kladniew B., Pérez A.A., Santiago L., Duran N., Castro G.R
Reactive and Functional Polymers
Volume 136, March 2019, Pages 122-130

Immobilized enzymes and their applications

Cacicedo M.L., Manzo R.M., Municoy S., Bonazza H.L., Islan G.A., Desimone M., Bellino M., Mammarella E.J., Castro G.R.
In: Advances in Enzyme Technology. Ram S. Singh, Reeta R. Singhania, Ashok Pandey and Christian Larroche
Elsevier LTD. Pp. 169-200. ISBN: 978-0-444-64114-4


Nanotechnology and Drug Delivery

Islan G.A., Martin-Saldaña S., Chevalier M.T., Alvarez V.A., Castro G.R. (2018) Nanotechnology and Drug Delivery. In: Talevi A., Quiroga P. (eds) ADME Processes in Pharmaceutical Sciences. Springer, Cham, pages: 135-165

  • Print ISBN978-3-319-99592-2   
  • Online ISBN978-3-319-99593-9

Self-Assembly Stereo-Specific Synthesis of Silver Phosphate Microparticles on Bacterial Cellulose Membrane Surface For Antimicrobial Applications

Bernardo Bayón, Maximiliano L.Cacicedo, Vera A.Álvarez, Guillermo R.Castro...
Colloid and Interface Science Communications:  Volume 26, September 2018, Pages 7-13


Bacterial Cellulose Hydrogel Loaded with Lipid Nanoparticles for Localized Cancer Treatment

ML Cacicedo, GA Islan, IE León, VA Álvarez, I Chourpa, E Allard-Vannier, ...
Colloids and Surfaces B: Biointerfaces 170, 596-608

Simple colorimetric method to determine the in vitro antioxidant activity of different monoterpenes

N Noacco, B Rodenak-Kladniew, MG de Bravo, GR Castro, GA Islan
Analytical biochemistry 55, 59-66

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: physicochemical characterization and in vitro/in vivo evaluation

SS Montoto, ML Sbaraglini, A Talevi, M Couyoupetrou, M Di Ianni, ...
Colloids and Surfaces B: Biointerfaces 167, 73-81

Optimization of culture conditions for kefiran production in whey: The structural and biocidal properties of the resulting polysaccharide

LM Blandón, MD Noseda, GA Islan, GR Castro, GV de Melo Pereira, ...
Bioactive Carbohydrates and Dietary Fibre

Hybrid bacterial cellulose-pectin films for delivery of bioactive molecules

ML Cacicedo, GA Islan, MF Drachemberg, VA Alvarez, L Bartel, ...
New Journal of Chemistry 42, 7457-7467

Biopolymers from Wastes to High-Value Products in Biomedicine

B Bayón, IR Berti, AM Gagneten, GR Castro
Waste to Wealth, 1-44


Development and tailoring of hybrid lipid nanocarriers

GA Islan, ML Cacicedo, B Rodenak-Kladniew, N Duran, GR Castro
Current pharmaceutical design 23 (43), 6643-6658

An introduction to Pharmacokinetics from conventional to advanced drug delivery systems

A Talevi, LB Blanch, GR Castro
Drug Delivery: An Integrated Clinical and Engineering Approach, 13-46

Drug delivery devices for infectious diseases

ML Cacicedo, GA Islan, P Gurman, GR Castro
Drug delivery: an integrated clinical and engineering approach., 347-370

Interaction of Solid Lipid Nanoparticles and specific proteins of the corona studied by Surface Plasmon Resonance

M Di ianni, GA Islan, CY Chain, GR Castro, A Talevi, ME Vela
Journal of Nanomaterials 2017 (Article ID 6509184), 1-11

Novel cheese production by incorporation of sea buckthorn berries (Hippophae rhamnoides L.) supported probiotic cells

A Terpou, AI Gialleli, L Bosnea, M Kanellaki, AA Koutinas, GR Castro
LWT-Food Science and Technology 79, 616-624

Cellulose-Containing Scaffolds Fabricated by Electrospinning: Applications in Tissue Engineering and Drug Delivery

A López-Córdoba, GR Castro, S Goyanes
Handbook of Composites from Renewable Materials, Nanocomposites: Advanced …

Design, characterization and in vitro evaluation of linalool-loaded solid lipid nanoparticles as potent tool in cancer therapy

B Rodenak-Kladniew, GA Islan, MG de Bravo, N Durán, GR Castro
Colloids and Surfaces B: Biointerfaces 154, 123-132

Hybrid inhalable microparticles for dual controlled release of levofloxacin and DNase: Physicochemical characterization and in-vivo targeted delivery to the lungs

GA Islan, ME Ruiz, JF Morales, AV Sbaraglini, Maria L., Enrique, G Burton, ...
Journal of Material Chemistry B 5, 3132-3144

Nanopharmaceuticals as a solution to neglected diseases: Is it possible?

GA Islan, M Durán, ML Cacicedo, G Nakazato, RKT Kobayashi, ...
Acta Tropica 170, 16-42

Desarrollo de bioimpresora 3D con 4to eje rotativo para uso en biotecnología, farmacología e ingeniería de tejidos

S Katz, B Bayón, GR Castro
I Workshop de Ciencia Abierta y Ciudadana-Argentina (La Plata, 2017)

Silver Nanoparticles for Treatment of Neglected Diseases

M Durán, WJ Fávaro, GA Islan, GR Castro, N Durán
Metal Nanoparticles in Pharma, 39-51

Emerging Technologies for Bioactive Applications in Foods

LG Santiago, CR Soccol, GR Castro
Food Bioactives, 205-226

Targeted Therapies (Editorial)

A Talevi, GR Castro
Mini-Reviews in Medicinal Chemistry 17 (3), 186-187



Kefiran-alginate gel microspheres for oral delivery of ciprofloxacin, Colloids and Surfaces B: Biointerfaces

Lina M. Blandón, German A. Islan, Guillermo R. Castro, Miguel D. Noseda, Vanete Thomaz-Soccol, Carlos R. Soccol,
Volume 145, 2016, Pages 706-715,
ISSN 0927-7765

Development of Crystal Violet encapsulation in pectin - Arabic gum gel microspheres,Reactive and Functional Polymers

Mariana V. Revuelta, M. Elizabeth Chacon Villalba, Alba S. Navarro, Jorge A. Güida, Guillermo R. Castro.
Volume 106, 2016, Pages 8-16,
ISSN 1381-5148

A simple green route to obtain poly(vinyl alcohol) electrospun mats with improved water stability for use as potential carriers of drugs,
Materials Science and Engineering: C

Alex López-Córdoba, Guillermo R. Castro, Silvia Goyanes
Volume 69, 2016, Pages 726-732,
ISSN 0928-4931

Progress in bacterial cellulose matrices for biotechnological applications, Bioresource Technology.

Maximiliano L. Cacicedo, M. Cristina Castro, Ioannis Servetas, Loulouda Bosnea, Konstantina Boura, Panagiota Tsafrakidou, Agapi Dima, Antonia Terpou, Athanasios Koutinas, Guillermo R. Castro.
Volume 213, 2016, Pages 172-180,
ISSN 0960-8524

Preparation And Characterization Of Polyvinyl Alcohol–pectin Cryogels Containing Enrofloxacin And Keratinase As Potential Transdermal Delivery Device

Guillermo R. Castro.
Volume 7, issue 8, 2016, Pages 640-645,

Smart lipid nanoparticles containing levofloxacin and DNase for lung delivery. Design and characterization

Germán A. Islan, Pablo Cortez Tornello, Gustavo A. Abraham, Nelson Duran, Guillermo R. Castro.
Volume 143, 2016, Pages 168-176.
ISSN 0927-7765

Advances in Chromobacterium violaceum and properties of violacein-Its main secondary metabolite: A review

Durán N, Justo GZ, Durán M, Brocchi M, Cordi L, Tasic L, Castro GR, Nakazato G.
Biotechnol Adv. 2016 Sep-Oct;34(5) 1030-1045.
doi:10.1016/j.biotechadv.2016.06.003. PMID: 27288924.

Development of antimicrobial hybrid mesoporous silver phosphate–pectin microspheres for control release of levofloxacin

Bernardo Bayón, Verónica Bucalá, Guillermo R. Castro,

Volume 226, 2016, Pages 71-78,

ISSN 1387-1811.

Modified bacterial cellulose scaffolds for localized doxorubicin release in human colorectal HT-29 cells

Maximiliano L. Cacicedo, Ignacio E. León, Jimena S. Gonzalez, Luismar M. Porto, Vera A. Alvarez, Guillermo R. Castro,

Volume 140, 1 April 2016, Pages 421-429

ISSN 0927-7765

Novel technologies for the encapsulation of bioactive food compounds

Liliana G. Santiago,  Guillermo R. Castro

Volume 7, 2016, Pages 78-85.

ISSN 2214-7993

Nanodevices for the immobilization of therapeutic enzymes

Valeria E. Bosio, Germán A. Islan, Yanina N. Martínez, Nelson Durán  & Guillermo R. Castro

Pages 447-464

ISSN 2214-7993

Construction and in vitro testing of a cellulose dura mater graft

Ezequiel Goldschmidt, Maximiliano Cacicedo, Sebastián Kornfeld, Marina Valinoti, Marcelo Ielpi, Pablo M. Ajler, Claudio Yampolsky, Jorge Rasmussen, Guillermo R. Castro & Pablo Argibay

Volume 38, 2016 - Issue 1

Advances in Chromobacterium violaceum and properties of violacein-Its main secondary metabolite: A review

Nelson Durán, Giselle Z. Justo, Marcela Durán, Marcelo Brocchi, Livia Cordi, Ljubica Tasic, Guillermo R. Castro, Gerson Nakazato.

Volume 34, Issue 5, 2016, Pages 1030-1045.
ISSN 0734-9750

A simple green route to obtain poly(vinyl alcohol) electrospun mats with improved water stability for use as potential carriers of drugs

Alex López-Córdoba, Guillermo R. Castro, Silvia Goyanes

Volume 69, 2016, Pages 726-732,
ISSN 0928-4931


Characterization of smart auto-degradative hydrogel matrix containing alginate lyase to enhance levofloxacin delivery against bacterial biofilms

German A. Islan, Cecilia Dini, Laura C. Bartel, Alejandro D. Bolzán, Guillermo R. Castro,

International Journal of Pharmaceutics,
Volume 496, Issue 2, 2015, Pages 953-964
ISSN 0378-5173


Self-assembly of carrageenin–CaCO3 hybrid microparticles on bacterial cellulose films for doxorubicin sustained delivery

Maximiliano L. Cacicedo, Karina Cesca, Valeria E. Bosio, Luismar M. Porto, Guillermo R. Castro,

Journal of Applied Biomedicine, Volume 13, Issue 3, 2015, Pages 239-248,
ISSN 1214-021x


Development of biopolymer nanocomposite for silver nanoparticles and Ciprofloxacin controlled release

German A.Islan, ArupMukherjee, Guillermo R.Castro

International Journal of Biological Macromolecules, Volume 72, 2015, Pages 740-750,
ISSN 0141-8130


Milk kefir: composition, microbial cultures, biological activities, and related products

Maria R. Prado, Lina Marcela Blandón, Luciana P. S. Vandenberghe, Cristine Rodrigues,
Guillermo R. Castro, Vanete Thomaz-Soccol and Carlos R. Soccol.

Frontier in Microbiology, 2015, Pages 22-41

Development and characterization of new enzymatic modified hybrid calcium carbonate microparticles to obtain nano-architectured surfaces for enhanced drug loading

G.A. Islan, M.L. Cacicedo, V.E. Bosio, G.R. Castro.

Journal of Colloid and Interface Science, Volume 439, 2015, Pages 76-87.
ISSN 0021-9797


Industrial Biorefineries & White Biotechnology

Licia M. Pera, Mario D. Baigori, Ashok Pandey and Guillermo R. Castro

Chapter 10 - Biocatalysis, In Industrial Biorefineries & White Biotechnology, Elsevier, Amsterdam, 2015, Pages 391-408.

ISBN 9780444634535